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Personality Disorders. Our website services, content, and products are for informational purposes only. The word comes from the mythical Chimera, a creature in Greek mythology that's part lioness, part goat, and part snake. Muhl has two immune systems - hers and her sister's. Hers is constantly trying to rid itself of the "foreign" system. In human beings, a chimera is a person who has two totally different sets of DNA inside their body. The strongest evidence for maternal infection increasing risk for a mental disorder in the offspring is the connection between schizophrenia and maternal respiratory infection [4,5]. A chimera is an organism whose cells are derived from two or more zygotes. Multiple-fetus pregnancies are not so rare, either. However, there were numerous reports supporting the hypothesis that immune activation is a risk for the onset of schizophrenia in adulthood [15,16]. February 15, 2023, 5:31 am, by For many chimeras, the mixing of DNA happens in the blood. 2010; 19: 1-12. PubMed: Brown AS, Cohen P, Harkavy-Friedman J, Babulas V, Malaspina D, et al. Nat Rev Neurosci. Howes OD, McCutcheon R. Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization. Quantification of fetal microchimeric cells in clinically affected and unaffected skin of patients with systemic sclerosis. But getting a better understanding of this condition can help improve the lives of those affected by it. The physiological significance of microchimerism is poorly understood. During pregnancy, a small number of cells from the fetus migrate into the mother's blood and travel to different organs. In this case, two different neuromediator-receptor groups will be present in the same brain tissue. Karens blood group was A positive with B traces. Autoimmune issues and flare-ups, as well as a variety of allergies. This spectacular image from the SPHERE instrument on ESO's Very Large Telescope is the first clear image of a planet caught in the very act of formation around the dwarf star PDS 70. one side has a different skin pigmentation color than the other side as a result of her twin's DNA. All this evidence points to the important role of neuro-inflammation and immune system in the pathophysiology of schizophrenia [14]. 36 days later, an Ultrasound showed a single fetus. 2018; 1-11. In House, doctors take up the case of a boy formed through . Chimerism. "But it's completely different. The man's previous child's DNA matched his, so . But the condition is believed to be quite rare. This test was used by IAAF from 1950 to 1992, to be replaced with testosterone levels test. Bob A. van Dijk et al. In some cases, the fetal cells remain in the mothers organs for years. In addition to expressing neural stem cell or immature neuron markers, FPCs were expressed mature neuron markers and indicated that they adopted a neuron fate. At the same time scientists played a recording of a warning call (threatening) or contact calls (non-threatening). Thus, FPCs appear to undergo a molecular and morphological maturation program similar to that observed during adult neurogenesis. Personality disorders are a group of mental illnesses. The procedure showed a sac with abnormal genitals, the histology examination confirmed the presence of ovary, fallopian tube, and uterus. Front Psychiatry. Chimera's meaning corresponds to it being a mix between separate types of animals, so you never know what they will do next! But, of course, it can't. The result? Their bodies contain two different sets of DNA. because as he later found out he had two sets of DNA. Transl Psychiatry. Avoidant personality disorder. As well as gold medals in the 2011 and 2012 world championship and Olympics, respectively.In 2009, Semenya was subjected to a sex test to reveal that she is an intersex woman, with an XY cell line in her body. In another recent story, a male chimera failed a paternity test because the DNA his child inherited came from the twin he absorbed in the womb. Thus, the fetal cells pass through the mothers body and have the opportunity to learn from the source the information acquired in the mother throughout human history. Narcissistic personality disorder. In mammals, the building blocks of brain development are completed before birth. Learn the causes of and treatment for hypertelorism, a wider than typical space between the orbits of your eyes. After delivery, the mothers immune system will neutralize those cells. AmJ Pathol. To date, about 100 cases of human chimerism are known. Given the capacity of DNA to store 2,5 billion terabytes of information, it should not be difficult to transfer the information acquired throughout human history to the new generation. Doctors are finding more and more instances of human chimeras a condition that might affect far more people than we realise. DOI: Rijnink EC, et al. In a. , researchers analyzed the brains of 59 women ages 32 to 101, after they had died. Microchimerism is a bidirectional exchange of fetal and maternal cells during pregnancy (Figure 1). Thus, numerous studies demonstrate that prenatal or early postnatal infections can result in both acute and persistent neurological and behavioral abnormalities in offspring resembling autistic traits or schizophrenia. An increase in the amount of viral infection and schizophrenia was detected in winter and spring. Taylor Muhl, I am my own twin. In the case of the Washington man reported this week, different genes were found in his cheek where the saliva in the test was taken from and his sperm. In appearance, although all keys and slots are similar, one key cannot start another car because the radiofrequency is different. Even if the dopamine produced by schizophrenic brain cells reaches nomadic cell reptors, it will not be able to bind because the rezonance frequency is different. Dilemma was a famous athlete in her time. In some cases, however, the fetal cells may stay in a woman's body for years. Twins: in a scientific report, there is a higher chance of microchimerism and chimerism with twins, doubles, or triples. Thus, there will be a relative abundance of dopamine in the environment. Depersonalization disorder, also called derealization disorder, is when you feel: Detached from your thoughts, feelings and body (depersonalization). 866.588.2264. Nat Rev Neurol. IVF ( In Vitro Fertilization) leads to a chimeric boy, with both male and female genitals. Similarly, a mother didnt pass a maternity test for the baby she gave birth to for the same reason: The DNA she presented in testing wasnt the same as the DNA she passed down to her children. Chimerism can occur due to fertilization error or twin absorption phenomena. She is not the mother of this one either. Artificial chimeras can also be created in labs. Natural chimeras can arise in various ways. The only option left was this DNA belongs to his vanished twin sister. However, they may have. Personality is the mindset, experiencing, and acting that distinguishes a person from other people. But the results showed that, genetically, she could not be the mother of two of her three children. Disputed maternity leading to identification of tetragametic chimerism, the New England Journal of Medicine, 2002. imperial college healthcare nhs trust jobs; But by wiggling around the egg, embryos can find the Goldilocks Zone which means they are able to shield themselves against extreme thermal conditions and produce a balanced sex ratio, according to the new study published in Current Biology journal. Schzophr Bull. She was accused of fraud, and authorities called for taking away her children. Significance of chimerism in hematopoietic stem cell transplantation: New variations on an old theme. Two different skin colors can also mean chimerism (Tylor Muhl). Chimerism can also affect nonhuman animals. Int J Eat Disord. Dependent personality disorder. Demirhan O, Ozturk N, Aydin N, Yildizdas HY, Demirbek B, et al. Only about 100 or so cases of chimerism have been recorded in modern medical literature. Their bodies contain two different sets of DNA. However, Drosophila melanogaster flies can have highly conserved molecular mechanisms despite human and all animal species, and many things can work similarly. Researchers have shown that even though neuronal coded ancestral behavior is not thought to be hereditary for generations, environmentally triggered modifications that of parental experiences, may allow the memory to remain hereditary. A more extreme form of chimerism can occur when a pair of twins is conceived and one embryo dies in the womb. Naturally acquired microchimerism; implications for transplantation outcome and novel methodologies for detection, Chimerism 2014. Scientists have identified a four-legged creature with webbed feet to be an ancestor of the whale. Chimerism carries the potential for disease as well as for health benefits. Schizophrenic clinical observations observed after bone marrow transplantation will significantly enhance our understanding of the importance of the immune system in schizophrenia [17,18]. Recently discovered by a team of international scientists, it was the largest land animal of its time, weighing 12 tons and standing at 13 feet. Current studies will provide valuable insights into the effects of the immune system on brain and behavior, and represent an important potential step towards more personalized medicine for patients with schizophrenia. Most mothers have cells from their babies growing in various parts of their body after pregnancy, and these cells can survive for at least . A.E. This is called artificial chimerism. The scientist couldnt confirm the association of this microchimerism and his autoimmune disease. People with this condition do not lose touch with reality. Therefore, the physiological task of Mc is a mysterious and incomplete issue. Tylor started an awareness campaign about chimerism. Still, some experiments involving placing human cells in other creatures have found limited success. (2004). Psychiatry Res. In genetics, chimerism is a biological condition and has nothing to do with monsters. Biol Psychiatry. These compartments are found beneath the skin, as well as lining the gut, lungs, blood vessels and muscles, and join together to form a network supported by a mesh of strong, flexible proteins, Working in the Brazilian state of Mato Grosso, a team led by archaeologists at the University of Exeter unearthed hundreds of villages hidden in the depths of the rainforest. Disputed maternity leading to identification of tetragametic chimerism. There are a few famous examples of human chimeras who only found out because of DNA testing . In science, the chimera indicates that an organism\human is made of two or more sets of cell lines (have two DNA sets in his\her body). Personality psychology is the study of how personality develops. 2017; 7: e1024. 5 . Camilla Drexler et al. The opposite may also happen, where a fetus absorbs a few cells from its mother. Permanently or temporarily. Today, transfused blood is usually treated with radiation. I believe Chimerism is responsible for multiple personality disorder, bipolar disorder, schizophrenia and auto-immune diseases like Lupus.. where a person's body attacks its own organs.. in other words, the antibodies think the organs are invaders because they are from the other chimera self. This is called tetragametic chimerism. 4. As part of the procedures, a DNA test was carried for Lydia and her children. Another mechanism is the fusion of more than one fertilized zygote in the early stages of prenatal development . People with personality disorders have trouble dealing with everyday stresses and problems. The DNA extracted from his cheek swab sample didnt match the DNA in his sperm sample. Studies have suggested that the condition might be present in 21 per cent of triplets, and eight per cent of twins. A 2015 study suggested that this happens in almost all pregnant women, at least temporarily. Vibration frequency, in a study on Drosophila melanogaster flies, the compartment where the hydrogenated apple essence, flies have always found the right. During development, there is a chance that entire organs will possess different genotypes. Tissue microchimerism is increased during pregnancy: A human autopsy study. 2018; 48: 2766-2778. Sigmund Freud laid the foundation for psychodynamic personality theories with his proposal of the id, the ego, and the superego. All this generally indicates that there is some extra environmental information that is transferred off-chromosomally to children. How Your Personality Type Affects Your Health. For example, the animal can end up with one organ made up entirely of cells of one genotype, and another organ completely built from cells of the other genotype. What they discovered were some previously unnoticed connections between neurotic personality traits and five illnesses; headaches, asthma, arthritis, peptic ulcers, and heart disease. 2019; 3: 1-6. They may remain in a mothers body or a childs body for a decade or more following childbirth. Summary. Chimeras will have all of the natural variety of the feline species. Multiple-fetus pregnancies are not so rare, either. Humans who are chimeras usually don't know it. In humans, chimerism most commonly occurs when a pregnant woman absorbs a few cells from her fetus. In 2002, Lydia Fairchild separated from her childrens father, Townsend. In a recent study, we reported that there was significant difference between women with postnatal depression and healthy women. They realize their perceptions aren't real. The sex test was based on the Y chromosomes presence or absence to indicate male or female gender. See also: 10 Gorgeous Sports Women Who Broke All Stereotypes. Tylor is the granddaughter of Edward Muhl (a vice president of Universal Studios). Plos Genetics. She was forced for a sex test; consequently, Dillema lost her national record (24.1 seconds) in the 200 m race. This review concerns natural human chimeras. Want to bookmark your favourite articles and stories to read or reference later? 2005-2023 Healthline Media a Red Ventures Company. https://www.ncbi.nlm.nih.gov/pubmed/23262442, https://www.ncbi.nlm.nih.gov/pubmed/15962317, https://www.ncbi.nlm.nih.gov/pubmed/20707697, https://www.ncbi.nlm.nih.gov/pubmed/18271969, https://www.ncbi.nlm.nih.gov/pubmed/19147820, https://www.ncbi.nlm.nih.gov/pubmed/18845390, https://www.ncbi.nlm.nih.gov/pubmed/15199216, https://www.ncbi.nlm.nih.gov/pubmed/11257233, https://www.ncbi.nlm.nih.gov/pubmed/25562580, https://www.ncbi.nlm.nih.gov/pubmed/25311587, https://www.ncbi.nlm.nih.gov/pubmed/26189694, https://www.ncbi.nlm.nih.gov/pubmed/19136031, https://www.ncbi.nlm.nih.gov/pubmed/28170004, https://www.ncbi.nlm.nih.gov/pubmed/24072812, https://www.ncbi.nlm.nih.gov/pubmed/26359903, https://www.ncbi.nlm.nih.gov/pubmed/28983259, https://www.ncbi.nlm.nih.gov/pubmed/30024883, https://www.ncbi.nlm.nih.gov/pubmed/29549549, https://www.ncbi.nlm.nih.gov/pubmed/29241049, https://www.ncbi.nlm.nih.gov/pubmed/29665879, https://www.ncbi.nlm.nih.gov/pubmed/20674602, https://www.ncbi.nlm.nih.gov/pubmed/22423165, https://www.ncbi.nlm.nih.gov/pubmed/24907222, https://www.ncbi.nlm.nih.gov/pubmed/24788841, https://www.ncbi.nlm.nih.gov/pubmed/27453085, https://www.ncbi.nlm.nih.gov/pubmed/25808647, https://www.ncbi.nlm.nih.gov/pubmed/25791080, https://www.ncbi.nlm.nih.gov/pubmed/27464490, https://www.ncbi.nlm.nih.gov/pubmed/30319639, Heighten Science Publications Inc. (HSPI), Creative Commons Attribution 4.0 International License. PubMed: Miyaoka T, Wake R, Hashioka S, Hayashida M, Oh-Nishi A, et al. The research, despite its. If the maternal cells that acquire physiopathological features participate in the production of the brain, there are 2 different groups of DNA in the brain. Copyright License: 2019 de Demirbek B, et al. Prenatal maternal mood patterns predict child temperament and adolescent mental health. It has a lot of different landscapes and we are trying to understand what's going on there. A chimera with a mixture of goat and sheep tissues, called a geep and having a goat's head but a sheep's woolly body, was reported in 1984. Tylors chimerism gave her some pathological side effects like autoimmune health issues, food and drug allergies, and jewelry sensitivities in varying degrees between her left and right sides. His blood grouping before the procedure showed that he was an AB group, but in an atypical way. Some studies have found thatfor every eight single-child births, at least one baby comes from a pregnancy that was originally multiple. Afterwards, these cells may pass back to the breast tissue and return to the baby with familial information they copy from the mother through breastfeeding. A chimera is an organism whose cells are derived from two or more zygotes. As a matter of fact, maternal cells pass from mother to fetus in the first 4.5 months of pregnancy due to viral infections of mother. A human chimera is a human with a subset of cells with a distinct genotype than other cells, that is, having genetic chimerism. Numerous animal studies demonstrate that prenatal or early postnatal infections can result in both acute and persistent neurological and behavioral abnormalities in offspring resembling autistic traits or schizophrenia [4,6]. Semenya is a middle-distance runner and the winner of the Olympic gold medal in 2016, gold medal of womens 800 m world championship in 2009 and 2017. During the first months of pregnancy, viral infections of the mother is disrupt the physiology. Chimeras have five different body parts - lion body, goat head, serpent tail, wings of an eagle, and a human head. These excavations included evidence of fortifications and mysterious earthworks called geoglyphs. Subsequent studies have shown that historical outbreaks such as influenza, measles, mumps, chicken pox and polio are associated with schizophrenia [9]. Breast Cancer Res. Both the fathers alleles were detected. Submitted: 30 October 2019 | Approved: 29 November 2019 | Published: 02 December 2019. In 2010, Chimerism journal reported a microchimerism case. Filiation: The fetus will leave cells in his mother the same way the mother will leave cells in her children. PubMed: Aydn M, Yiit EN, Vatandalar E, Erdoan E, ztrk G. Transfer and Integration of Breast Milk Stem Cells to the Brain of Suckling Pups. Kidneys are complex organs, so it can be difficult to find a donor for a transplant. In the study, a person unknown to the wild jackdaws approached their nest. Chimeras are typically seen in non-human zoology, but also discovered to a rare extent in humans. Yu N, et al. After birth, a boy was investigated and confirmed as a normal boy. In science, the chimera indicates that an organism\human is made of two or more sets of cell lines (have two DNA sets in his\her body). Tetragametic chimerism sounds like you have cancer- human chimera just makes you sound cool. MMc prevalence was significantly greater in women with postnatal depression than control groups [32]. Today, however it is not known exactly why Mc exists or what its task is. Human Immunology, 2001. Fet-maternal cell migration can explain the concept of hallucination. Arthrogryposis is a congenital condition present at birth characterized by a stiffening of the joints. The eight traits identified in this manner are as follows: domineering, vindictive, cold, socially avoidant, nonassertive, exploitable, overly nurturant, and intrusive . The man had absorbed his unborn twin brothers genes in the womb. Male tortoiseshell cats are often chimeras. 2016; 55: 709-716e2. Bull World Health Organ. Then, these cells all fuse together into one human embryo with crossed cell lines. Pregnancy-related migratory progenitor fetal cells (FPCs) have been shown to merge with multiple maternal organs. Recipients of tissue and organ transplants are artificial chimeras. Although schizophrenia was considered a syndrome of different biological backgrounds, the inclusion of immune system disorders may be one of the common mechanisms. "Before New Horizons, everyone thought Pluto was going to be a netball - completely flat, almost no diversity," said Tanguy Bertrand, an astrophysicist and planetary scientist at NASA's Ames Research Center and the lead author on the new study. Pregnancy: pregnant mothers have few fetus cells that escape to their blood circulation and then to various tissues. In other cases, their bone marrow may match the DNA of their donor only. 2019; 3: 042-046. Each population of cells keeps its own genotype and its own characters. Kamlesh Madan, natural human chimeras: a review, European Journal of Medical Genetics, 2020. In reality, chimerism is no where near as mystical; it is simply characterized by one organism made up of at least two different genotypes - or two separate sets of genes. Top 10 Already Existing Human Chimeras Which Could Include You! Today, we must recognize that maternal microchimeric cells cause autoimmune diseases, and that these cells are the etiologic cause of alloimmune diseases, and should be treated accordingly (also in psychiatric diseases). Last week, researchers led by Spanish scientist Juan Carlos Izpisua Belmonte announced they had created the first human-monkey chimera embryos in China. Chimerism and tetragametic chimerism in humans: Implications in autoimmunity, allorecognition and tolerance. The condition can mean that people aren't genetic mothers of children they've given birth to, and that people can have two . There is also a kind of chimerism, called microchimerism, that particularly affects pregnant women. You may: Blood transfusion: this procedure include the transfer of red blood cells RBCs; as general information, RBCs contain no DNA, or nucleus to be precise. In a recent study; it was confirmed that maternal cells were detected in the blood and brain of the offspring and that these cells differentiated into both neuron and glia cells in the brain [1]. Lisa Strain et al. Therefore, it is important to examine the impact of parental experiences affecting future generations. Male cellmicrochimerism in normal and diseased female livers from fetal life to adulthood. obesity. Annular pancreas is an extra ring of pancreatic tissue surrounding the small intestine. How common is it? [MIM:600072]. 2015; 48: 512-516. The symptoms of chimerism vary from person to person. However, the association of these fetal cells (FCs) with the brain, their long-term survival and differentiation are not fully known. Ankara niversitesi, Tp Fakltesi Mecmuas. Examples of multifactorial inheritance include. Signup for our newsletter to get notified about our next ride. The production of each DNA is individual. Chimras could bridge the gap between treatment and cure or are they your silent and deadly twin? Camilla Drexler et al. Experts arent sure how many human chimeras exist in the world. Hollywood TV shows have a few examples of chimerism. In this context, chronic stress conditions affect pregnant women [24]. The relationship between maternal infection and neurodevelopmental disorders has long been known. She and her family members did a histocompatibility testing. He said, I thought it was pretty incredible that I can disappear and someone else appears.. The next time jackdaws saw this same person, the birds that had previously heard the warning call were defensive and returned to their nests more than twice as quickly on average. Biol Psychiatry. However, FPCs were shown to mature and differentiate into neurons in the mother brain. Blood group chimerism, current opinion in hematology 2006. PubMed: Sawaya HHB, Jimenez SA, Artlett CM. The word chimera comes from the ancient Greek, meaning 'she-goat' or 'monster'. Personality disorders are a group of a 10 mental health conditions that involve long-lasting, disruptive patterns of thinking, behavior, mood and relating to others. Some studies have found thatfor every eight single-child births, at least one baby comes from a pregnancy that was originally multiple. During the months of winter and spring when the incidence of viral infections as well as the incidence of schizophrenia births are high, supporting our hypothesis [14]. In this case, dopamine will reach and activate the hearing receptors and the schizophrenic person will hear it as a sound. Chimera is a Greek mythological monster with a lion head, goat head protruding from the midbody, snake tail (sometimes identified as a dragon) with dragon wings. Pregnancy is the most common and natural cause of chimerism, and bi-directional trafficking of hematopoietic cells occurs through the placenta. An animal chimera genetic engineering is a single organism made up of two or even more genetically different populations of cells originating from various zygotes engaging in sexual reproduction. Prenatal rubella, premorbid abnormalities, and adult schizophrenia. The paper concluded that the child was a chimera. Human fertility treatments like IVF and multiple embryo transfer, which sometimes can cause double pregnancies and twins. But you might get a diagnosis of BPD/EUPD if these feel consistently unstable or intense and cause you significant problems in daily life. Because a personality disorder is difficult to diagnose . Sci Rep. 2018; 8: 14289. In other cases, human chimeras develop when two different sperm cells fertilize two different egg cells. In Greek mythology, the chimera is represented by a monster with a goat's body, a head and a neck of a lion and a snake's tail. 2014;219: 353-360. Blood group chimerism in human multiple births is not rare, American Journal of Medical Genetics, volume 61, issue 3, 1996. But people may go their entire life without knowing they are chimeras because the condition is rare and people arent usually tested for it. JAutism Dev Disord. These include Dissociative Identity Disorder, Other Specified Dissociative Disorder 1-a, and Other Specified Dissociative Disorder 1-b. Therefore, nomadic cell receptors will continue to demand dopamine due to dopamine hunger and dopamine will be continuously produced and delivered. (It's worth noting that real-life human chimeras do not look like supernatural beings.) The blood DNA is from immunological cells. Genetically, he was his sons uncle. There are treatment options to help. However, a condition where two or more populations of genetically distinct cells emerge in the same zygote is called a mosaic, rather than a chimera. A version of the condition called artificial chimerism can also occur through transfused blood stem cells though that is less common because transfused blood now tends to be hit with radiation to help the host absorb it or through bone marrow transplantation. Qiong Yu et al. This is because the extra DNA they receive links the trait for their coloration to infertility. In biology, the term has come to refer to any organism that contains more than one set of genes. (n.d.). Join thought-provoking conversations, follow other Independent readers and see their replies. For cases of chimerism that cause intersex features, theres a risk of infertility. In science, an AB child can only generate for A and B parents, and for a Parent with O blood group, it is impossible to give an AB child.The researcher carried out a gene search the found A, B, and O alleles. While the mission of chimerism is straight forward, the subject is profound. Effect of fetal microchimeric cells on the development of postnatal depression. The findings support the likelihood that fetal cells frequently cross the human blood-brain barrier and that Mc in the brain is relatively common. Siblings: maternal siblings can have traces of each other DNA, which their mother possibly delivers. It's a bit less dramatic than a fire-breathing monster, sure, but it's still pretty wild. The Chimera may be ancient Greece's most bizarre creatureso bizarre that its name is now used to describe any creature with an unusual combination of animal traits. They involve long-term patterns of thoughts and behaviors that are unhealthy and inflexible. Genetic tests can help uncover whether or not a persons blood cells contain DNA thats not present in the rest of their bodies. A small number of chimera stories have appeared in popular news headlines over the past few decades. Early life programming and neurodevelopmental disorders. PubMed: Pickles A, Sharp H, Hellier J, Hill J. Prenatal anxiety, maternal stroking in infancy, and symptoms of emotional and behavioral disorders at 3.5 years. Rheumatology. In 2017, scientists from the Salk Institute for Biological Studies in La Jolla, California, grew human cells in pig embryos to create, In fact, researchers from the University of Minnesota later managed to grow. It may occur randomly or be inherited from a parent. Pictures of chimera animals often show creatures that looks stitched together . The study concluded that the woman was a chimera with a fusion of AO genotype half and BO genotype half. It could be becoming more common with certain fertility treatments like in vitro fertilization, but this isnt proven. Disruption of neurodevelopmental pathways can affect cognitive and mental disorders as well as affect future brain function and may increase the risk of neurodevelopmental and psychiatric disorders in later life [23]. (2009). A Japanese scientist advances the development of plasma thrusters, which could boost spacecraft deep into space, by improving their conversion efficiency. Immune mediators in the brain and peripheral tissues in autism spectrum disorder. Using chimera to describe a human with two different types of DNA in the same body does not imply they are monsters. During pregnancy, a small number of cells from the fetus migrate into the mother's blood and travel to different organs. Disconnected from your environment (derealization).